Pre-announcement: Research call on AMR diagnostics and surveillance

We are pleased to pre‐announce the transnational call Development of innovative strategies, tools, technologies, and methods for diagnostics and surveillance of antimicrobial resistance.

This call aims to fund research projects developing novel or improving existing strategies, tools, technologies and methods for diagnosis and/or One Health AMR surveillance. It involves 21 funding organisations from 18 countries and has a total estimated call budget of 18,8 M€.

The call opens on 10 January 2023.

Read more on the call page

Shadows of people on a colourful background.

Six new networks the area of diagnostics and surveillance

Six networks have been recommended for funding within the JPIAMR 15th transnational call: Diagnostics and Surveillance Networks. The networks include 228 partners from 40 countries and the total funding amount is 300 000 € plus up to 100 000 € fort start-up and final joint workshops.

The networks assemble leading experts and stakeholders with an intent to facilitate the development, optimisation and use of diagnostic and surveillance tools, technologies and systems.

For the first time, a network focussed on antifungal resistance has been included.

Learn more about the networks

Northern lights

New projects in the area of therapeutics

Thirteen projects involving 72 partners from 15 different countries have been recommended for funding within the JPIAMR 14th transnational call: Disrupting drug Resistance Using Innovative Design. The call was within the framework of the ERA‐NET JPIAMRACTION and the total funding amount is 15,4 M€.

The projects aim to improve the treatment of bacterial and fungal infections (including co-infection) and/or the prevention of the emergence/spread of resistance in humans, animals or plants through the improvement of the efficacy, specificity, delivery, combinations and/or repurposing of drugs and plant protection agents.

Learn more about the projects

Reports from DESIGN OH AMR consultations available

In 2022, the Coordination and Support Action (CSA) DESIGN OH AMR has organised a series of stakeholder and expert consultations to collect input to the update of the research and innovation objectives within the JPIAMR Strategic Research and Innovation Agenda (SRIA). This serves in preparation for the Horizon Europe candidate One Health AMR Partnership.

The reports from the consultations are now available for download.

Illustration of the Globe with people and animals

Survey on funding instruments by the future OH AMR Partnership programme

The JPIAMR has since its launch in 2011 coordinated 13 transnational joint calls till date supporting 99 projects and 38 networks with over 1300 researchers by investing 125 million Euros. In the framework of the CSA DESIGN, JPIAMR is preparing for the future One Health Antimicrobial Resistance (OH AMR) partnership programme including its portfolio for funding instruments. The OH AMR partnership programme will be a research and innovation (R&I) funding programme designed and launched jointly by the European Commission and member states. Using a combination of EU and national public R&I funding, this new programme will contribute to the European One Health Action Plan against AMR and the WHO Global Action Plan on AMR, both aiming to reduce the threat of antimicrobial resistance (AMR).

The aim of this survey is to gather feedback from the AMR research community to understand its views regarding gaps in the AMR funding landscape, and, the requirements for potential funding mechanisms with impact. These funding instruments could be used by JPIAMR member states and the European Commission in the future co-funded programme OH AMR partnership to support R&I and capacity building activities.

Link to survey: https://survey.vr.se/fundinginstrumentsOHAMR

The survey will close on the 26th September 2022 at 12.00 CEST

Pills on green background

Main achievements of Therapeutics research projects and networks

A report on the outputs, outcome and impact generated by the projects funded in the various JPIAMR transnational research project and network calls under the Therapeutics priority topic has been published.

This report has been prepared using information provided by the coordinators of the research projects and networks in the mid-term and the final term progress reports. The aim is to disseminate information about the outputs and the outcomes of the funded projects and networks to highlight the promising results of the funded research. Some highlights from the report on the main achievements of the Therapeutics research projects and networks and the impact generated are:

  • The JPIAMR discovery pipeline resulting from the funded research projects has a high level of diversity including direct acting molecules, potentiators or enablers, anti-virulence agents, repurposed agents, phage and nanobiotics.
  • Six new candidates/leads have been identified and five patents have been filed.
  • In addition to the peer-reviewed scientific articles in highly-recognised journals, the research projects and networks have also published white papers, roadmaps and position papers that can contribute to evidence-based policymaking.

Download the report: JPIAMR therapeutics discovery pipeline: Outputs, outcomes and impact of the funded projects and networks in the Therapeutics priority topic of the JPIAMR-SRIA (pdf 0,8 MB)

Social sciences as a cross-cutting theme in JPIAMR research priorities

The development of resistance to antibiotics is a biological process, but the context that determines emergence and impact of resistance is underpinned by social aspects. Therefore, it is necessary to identify, understand and evaluate these social aspects to enable the prevention and control of AMR.

Using the One Health approach means it is vital to include social processes across human and animal health care, in the food production chain and in environmental protection. Questions to ask are, for example: How do farmers, vets, and regulatory systems manage livestock production? How do regulatory and fiscal frameworks incentivise or deter antimicrobial development, production, availability, and use? How do the public and healthcare professionals understand, value, and use antimicrobials?

There is a need for clearer descriptions of how different social scientific fields – economics, political science, ethics, sociology, anthropology, and law – could deepen the understanding of the AMR issue, and also the value from particular methods such as interviews or ethnography. Once the definition, scale, and scope are understood, we can begin to fully understand the potential contribution of perspectives based on the social sciences.

To start introducing social sciences as a cross-cutting theme in the JPIAMR Strategic Research and Innovation Agenda (SRIA) it is necessary to develop a list of key areas to focus on. It will also be necessary to develop quality assessment criteria that are sufficiently broad to capture the range of quantitative and qualitative methods used by social sciences but specific enough to enable a systematic critique. This exercise will also contribute to the development of the candidate Horizon Europe co-fund OH AMR Partnership.

This initiative is led by professor Katherine Payne, University of Manchester, United Kingdom. An expert group has been appointed, consisting of:

  • Alex Broom, University of Sydney, Australia
  • Anja Schreijer, Erasmus University, The Netherlands
  • Claire Harpet, Université Jean Moulin Lyon 3, France
  • Ian Donald, University of Liverpool, United Kingdom
  • Jon Pierre, University of Gothenburg, Sweden
  • Jonathan Rushton, University of Liverpool, United Kingdom
  • Richard Smith, University of Exeter, United Kingdom
  • Clare Chandler, London School of Hygiene & Tropical Medicine, United Kingdom

The group is currently drafting a working paper that will be sent for wider consultation among experts before being included in the SRIA revision process.

Consultation: antiparasitic and antiviral resistance

The JPIAMR has launched a round of consultation on antiparasitic and antiviral resistance. The information will be used for outlining research and innovation priorities in the Strategic Research and Innovation Agenda (SRIA) on Antimicrobial Resistance and informing the scope and direction of the candidate One Health AMR partnership. 

The (SRIA) presents an overview of recent developments and future needs for AMR research. More information and the link to the SRIA can be found here: JPIAMR Strategic Research and Innovation Agenda. The surveys have aim to map national and international funding in the area of antiparasitic and antiviral resistance.

National/country level funding survey

This survey has been designed to collect national input in extending the scope of the candidate One Health AMR partnership to include antiparasitic and antiviral resistance, and to show national willingness to commit funds to future activities dedicated to those topics. The survey should be submitted by national representatives only (one survey per country is expected).

Link to survey: https://survey.vr.se/Survey/773

A word template of the survey can be downloaded here and circulated for national consultation before submission: National/country level funding survey (Word file)

The outcomes of this survey will have an important impact on the future scientific directions taken by the JPIAMR and by the candidate OH AMR Partnership.

The survey will close on the 6th June 2022 at 12.00 CEST.

International funding survey

This survey has been designed to collect information on the international funding landscape for antiparasitic and antifungal research. The survey should be submitted by representatives from international funding organisations only (one survey per organisation is expected).

Link to survey: https://survey.vr.se/Survey/775

A word template of the survey can be downloaded here and circulated for organisational consultation before submission: International funding survey (Word file)

The outcomes of this survey will have an important impact on the future scientific directions taken by the JPIAMR and by the candidate OH AMR Partnership.

The survey will close on the 30th May 2022 at 12.00 CEST.

Illustration of Candida auris

Review from the JPIAMR SRIA fungal resistance group published in Nature Reviews Microbiology

JPIAMR is pleased to share the following review that was published in Nature Reviews Microbiology: Tackling the emerging threat of antifungal resistance to human health. The review was written by the expert group on antifungals that led the broadening on the JPIAMR Strategic Research and Innovation Agenda in 2021.

“Our review articulates the neglected aspect of antifungal resistance, and outlines where attention is needed to address this burgeoning problem. In particular, One-Health drivers require specific policy-led attention as it is here that agricultural practice conflicts with public health necessities – we hope that our article will focus attention on these increasingly urgent issues.” – Mat Fisher, Imperial College London, UK

The JPIAMR Strategic Research and Innovation Agenda was broadened in 2021 to include antifungal priorities for research and innovation.

“The article marks an important change in the JPIAMR Strategic Research and Innovation Agenda, which now incorporates antifungal resistance in its research goals. Fungal resistance proposals are eligible for funding in current and future calls, thereby enabling the international scientific community to address increasing challenges regarding the epidemiology, diagnosis and management of antifungal resistance.” – Paul E. Verweij, Radboud University Nijmegen Medical Center, the Netherlands

Scientific Research and Innovation Agenda picture

Strategic Research and Innovation Agenda – global survey

The JPIAMR has launched a round of public consultation on the Strategic Research and Innovation Agenda (SRIA) on Antimicrobial Resistance.  The (SRIA) presents an overview of recent developments and future needs for AMR research. More information and the link to the SRIA can be found here: JPIAMR Strategic Research and Innovation Agenda

The updated SRIA outlines five key priority topics within the AMR field: Therapeutics, Diagnostics, Surveillance Transmission and Evolution, and Prevention and Intervention.

The SRIA is a prime guiding tool for AMR research prioritisation in investments, research activities and planning for JPIAMR member states and other funding initiatives. It is also one of the most thorough guidelines on AMR research, helping researchers, policymakers, media, educators, health workers and the scientific community to work together on solutions to curb AMR on a global scale.

You can contribute to the consultation by completing the following survey: JPIAMR SRIA global survey

The survey will be closed on 15th April 2022 at 12.00 CET.