Projects
JPIAMR supports research projects and networks that enable researchers to collaborate across national and scientific borders to find new treatments, solutions and methods to tackle AMR. It supports a large portfolio from 20 therapeutic candidates in the pipeline, to new knowledge on selection and transmission dynamics of AMR in a One Health context, the design of new interventions or new surveillance studies, standards and protocols.
Projects

Projects

JPIAMR supports research projects and networks that enable researchers to collaborate across national and scientific borders to find new treatments, solutions and methods to tackle AMR. It supports a large portfolio from 20 therapeutic candidates in the pipeline, to new knowledge on selection and transmission dynamics of AMR in a One Health context, the design of new interventions or new surveillance studies, standards and protocols.

Supported JPIAMR projects and networks

JPIAMR has coordinated 13 transnational joint calls till date supporting 99 projects and 38 networks with over 1300 researchers by investing 125 million Euros within the six priority areas of the shared JPIAMR Strategic Research and Innovation Agenda (SRIA) with a One Health approach.

Explore the JPIAMR project database that presents interactive data on projects and networks supported under the various calls coordinated by the JPIAMR.

Click on the titles below for more information on the research activities and outcomes of the projects and the networks supported under the JPIAMR framework.

The JPIAMR six Priority topics are:

Diagnostics

Environment

Interventions

Surveillance

Therapeutics

Transmission

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Antimicrobial Stewardship in Hospitals, Resistance Selection and Transfer in a One Health Context (STRESST)

Environment

Interventions

Surveillance

Transmission

The transfer of antibiotic residues and antibiotic resistant bacteria into the environment and subsequently into animal drinking water may have an effect on the transmission of resistant bacteria and their resistance genes back into the human population. This holistic One Health view of antibiotic resistance is at the heart of our project. We want to […]

Specific Targeting of Antimicrobial Resistant Strains in situ using Targeted-Antibacterial-Plasmids (STARS-TAP)

Environment

Interventions

Therapeutics

Transmission

The global spread of antimicrobial resistance (AMR) among pathogenic bacteria is recognized as one of the biggest concerns in public health and a research priority in microbiology. Drug-resistance increases exponentially for certain bacterial organisms and is becoming the main threat to human health worldwide. As a consequence, national and international authorities have emphasized the need […]

Strengthening implementation of National Action Plans through a One Health AMR full economic costing exercise (SNAP ONE)

Interventions

Surveillance

Therapeutics

Transmission

Antibiotic resistance costs lives and money. Yet if we don’t have a good grasp of the numbers we will never know where it lies in terms of our other national priorities. In Africa we have especially little evidence on how people, animals, and the environment are affected by it. So those who make decisions do […]

Selecting Efficient Farm-level Antimicrobial Stewardship Interventions from a one health perspective (SEFASI)

Environment

Interventions

Surveillance

Transmission

Antimicrobial resistance (AMR) links together people, plants, animals and their environments under the One Health umbrella. In this work we will similarly link interventions aimed at AMR by considering their impact not only in terms of impact on hospitals, communities or farmers, but across all of these groups. This is key to informing optimal intervention […]

Phage Therapy to Reduce AMR Enterobacteria Spread from a One Health Perspective (Phage-Stop-AMR)

Diagnostics

Environment

Interventions

Transmission

The spread of multi-drug resistant (MDR) bacteria in food-producing animals including broilers is a global public health concern. Controlling growth of MDR bacteria and limiting the transmission of antimicrobial resistance genes in broilers could be an effective mitigation strategy. To counteract the spread of MDR bacteria among zoonotic pathogens in food-producing animals and reduce the […]

Phage treatment and wetland technology as intervention strategy to prevent dissemination of antibiotic resistance in surface waters (PhageLand)

Environment

Interventions

Surveillance

Transmission

PhageLand is aimed to develop a novel intervention strategy combining the low-cost and eco-friendly capacity of constructed wetlands with the specificity of bacteriophages (i.e., viruses killing bacteria) to prevent the dissemination of antibiotic resistance from wastewater into surface waters. PhageLand will investigate the prevalence of antibiotic resistant bacterial pathogens (ARB) in low-middle income countries (LMICs) […]

Interventions to decrease CRE colonization and transmission between hospitals, households, communities and domesticated animals (I-CRECT)

Environment

Interventions

Surveillance

Transmission

In middle-income countries antibiotic resistance is increasing causing suffering and high mortality. In 12 Vietnamese hospitals half of patients were colonised with “superbugs” called carbapenem resistant Enterobacteriaceae, for short CRE , at admission 13% and after 2 weeks in hospital 89%. CRE colonization cause hospital infections and high mortality. As many patients are CRE colonized […]

Use of phage applications to combat MRSA at the sow-piglet interface to reduce exposure of staff and contamination of the environment (PHAGE-EX)

Environment

Interventions

Transmission

This project addresses the issue of occupational and environmental exposure to livestock-associated MRSA in pig farms. Using bacterial phages, we will try to reduce the transmission of MRSA from sows to their piglets during the nursing phase. Specific phage cocktails will be designed using several phages to control MRSA on the skin of sows and […]

Novel interventions for eliminating one-health mobile antimicrobial resistance genes from human and animal microbiomes (MOB-TARGET)

Interventions

Transmission

Many of the most important one-health AMR genes are carried on mobile genetic elements that move between bacterial strains through the process of conjugation. The genetic mobility of these AMR genes allows them to become widely disseminated across species of bacteria, including harmless commensal strains and dangerous pathogen strains, and ecological niches, including humans, farms […]

Microbiota Intervention Strategies Limiting Selection and Transmission of Antibiotic Resistance burden in the One Health domain (MISTAR)

Diagnostics

Interventions

Surveillance

Transmission

The central aim of MISTAR is to implement and quantify the effect of novel intervention strategies based on the preservation of the “healthy microbiota” to eradicate and control the spread of antimicrobial resistance (AMR). We will do this using a One Health approach that involves hospitalized patients, healthy humans, pets, farm animals and the environment. […]