Topic: Therapeutics

The Call on knowledge transfer of research on Aquatic Pollutants will be part of the AquaticPollutants ERA-Net Cofund action and support the AquaticPollutants cofunded call projects. The objective is to realize a better and wider dissemination, develop new innovative methods to support the transfer of research and the uptake of results into the public and administrative sector, policy, industry or economy. This will lead to a greater and focused impact and increase the awareness of projects’ outcomes. Moreover, cross-cutting issues, that address all transnational projects alike, can better be dealt with. The implementation of a knowledge transfer project will in addition lead to a better alignment of the three participating JPIs and improve their collaboration possibilities.

Proposals should be built by a consortia of German, French and Swedish institutions. The total budget of the call is approximately 1,050,000 Euro

Information & application

This call is closed.

Call text, updated 2020-03-17 (pdf 0,4 MB). All specific information on the Call on knowledge transfer of research on Aquatic Pollutants.
National regulations, updated 2020-03-17 (pdf 0,3 MB)

Call Secretariat and National points of contact

The Call on knowledge transfer of research on Aquatic Pollutants is hosted by Project Management Jülich.

National points of contact:

Germany
Stefanie Pietsch: s.pietsch@fz-juelich.de
Sabine Sorge: s.sorge@fz-juelich.de

France
Tristan Lescure, tristan.lescure@anr.fr

Sweden
Anna Maria Fleetwood: amf@vr.se
Patriq Fagerstedt: Patriq.Fagerstedt@vr.se

Funders

France
French National Research Agency (ANR)

Germany
The Federal Ministry of Education and Research (BMBF)

Sweden
Swedish Research Council (SRC)

Supported projects

The project AquaticPollutantsTransNet was funded in the call on knowledge transfer of research on Aquatic Pollutants. The project is a consortium of four partners (two French, one German and one Swedish). Click on the project title below to learn more.

Aquatic Pollutants

The three Joint Programming Initiatives (JPIs) on Water, Oceans and Antimicrobial Resistance (AMR) are pleased to announce a joint transnational call for research and innovation projects on risks posed to human health and the environment by pollutants and pathogens present in the water resources.

The call AquaticPollutants will support research and innovation projects that establish integrated and cross-sectoral approaches for risk-management combining the research areas of contaminants of emerging concerns (CECs), pathogens and antimicrobial resistance. The whole water cycle, from the source through the river basins and eventually to the estuaries and oceans, has to be considered. The projected call budget is approximately 25 million Euro (co-funded by the European Commission).

There are still major risks associated with the occurrence of emerging contaminants, pathogens and antimicrobial resistant bacteria in our water bodies and oceans. To face these challenges in a comprehensive way and to develop multidisciplinary and practical solutions for the provision of safe drinking water and healthy aquatic environments, this Joint Transnational Call (JTC) aims to make the research communities in the freshwater, marine and the health sectors work together and create synergies for joint approaches.

Call themes

Measuring – Environmental behaviour of contaminants of emerging concern (CECs), pathogens and antimicrobial resistant bacteria in aquatic ecosystems
Evaluating – Risk assessment and management of CECs, pathogens and antimicrobial resistant bacteria from aquatic ecosystems (inland and marine) to human health and environment
Taking Actions – Strategies to reduce CECs, pathogens and antimicrobial resistant bacteria in aquatic ecosystems (inland and marine)

Information & application

Timeline

Due to the high numbers of pre-proposals submitted and summer holiday season across Europe, the evaluation phase of the pre-proposals had to be prolonged. The guidelines for full-proposal submission and new timeline are now available (see below). The Submission platform is also now open.

Call opening: 17 February 2020
Deadline pre-proposals: 18 May 2020, 17.00 CET
Invitation to submit full proposals: 19 October 2020
Deadline full proposals: 23 November 2020
Funding decision announced: March 2021
Start of projects: 2021
Project ends: 2024

Application

This call is closed.

AquaticPollutants call – Call text – updated 18 March 2020 (pdf). All specific information on the call AquaticPollutants.
AquaticPollutants call – National regulations – updated 20 April 2020 (pdf)
AquaticPollutants call – National contact points

Support for applicants

Information Webinar for Applicants : 12 March 2020, 13 – 14.30, online. Click here for the webinar presentation: AquaticPollutants webinar presenation (pdf)
AquaticPollutants call – Guidelines for pre-proposal submission (pdf)
AquaticPollutants call – Guidelines for full-proposal submission (pdf)
AquaticPollutants F&Q (pdf)

Call Secretariat

The AquaticPollutants Call Secretariat is hosted by Project Management Jülich.

Contact:
Stefanie Pietsch, s.pietsch@fz-juelich.de
Sabine Sorge, s.sorge@fz-juelich.de

Funders

Belgium
Belgian Science Policy Office (BELSPO)
Fonds de la Recherche Scientifique (FNRS)
The Research Foundation – Flanders (FWO)

Brazil
Conselho Nacional das Fundações Estaduais de Amparo à Pesquisa (CONFAP)

Cyprus
Research and Innovation Foundation (RIF)

Czech Republic
Technologická Agentura České Republiky (TAČR)

Denmark
Innovation Fund Denmark (IFD)

Estonia
Eesti Teadusagentuur (ETAg)

Finland
Academy of Finland (AKA)

France
French National Research Agency (ANR)

Germany
The Federal Ministry of Education and Research (BMBF)

Greece
General Secretariat for Research & Technology (GSRT)

Ireland
Environmental Protection Agency (EPA)

Israel
Ministry of Health – Chief Scientist Office (CSO-MOH)

Italy
Agenzia Regionale per la Protezione dell’Ambiente Regione Siciliana (A.R.P.A. Sicilia)
Ministero dell’Università e della Ricerca (MUR)

Latvia
Ministry of Education and Science (IZM)

Moldova
National Agency for Research and Development (NARD)

Norway
The Research Council of Norway (RCN)

Poland
National Centre for Research and Development (NCBR)

Portugal
Foundation for Science and Technology (FCT, I.P.)

Romania
Executive Agency for Higher Education, Research, Development and Innovation Funding (UEFISCDI)

Scotland
Scottish Enterprise (SCOTENT)

South Africa
Water Research Commission (WRC)

Spain
Agencia Estatal de Investigación (AEI)
Instituto de Salud Carlos III (ISCIII)

Sweden
Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS)
Swedish International Development Cooperation Agency (Sida)
Swedish Research Council (SRC)

Taiwan
Ministry of Science and Technology (MoST)

Tunesia
Ministry of Higher Education and Scientific Research (MHESR)

Turkey
The Scientific and Technological Research Council of Turkey (TUBITAK)

Supported projects

Eighteen projects including 103 partners were funded within the AquaticPollutants Joint Transnational Call. The total funding amount was approx. 20 M€. Click on the project titles in the list below to read more on each project.

JPIAMR Network Plus 2020

The JPIAMR is launching the tenth call for transnational networks in partnership with eight member countries; Canada, France, Italy, Latvia, the Netherlands, Norway, Spain, and Sweden.

The intent of the call “JPIAMR Network Plus 2020” is to support networks to design and implement ways to support AMR research considering at least one of the six strategic areas of the JPIAMR Strategic Research and Innovation Agenda (SRIA): Therapeutics, Diagnostics, Surveillance, Transmission, Environment and Interventions. Networks should develop and implement activities focusing on AMR within the domains of Human health, Animal health and the Environment. The Networks are encouraged to bridge multiple One Health areas as needed and to consider the incorporation of their activities within the JPIAMR-Virtual Research Institute (JPIAMR-VRI).

Networks will be funded with €50,000-100,000 per year per Network for one to two years, to connect experts from research performing organisations and establish expertise clusters in the AMR community. Networks may build upon new or existing global collaborations/partnerships. The total budget of the call is approximately 940,000 Euro.

The formation of larger, multi-coordinator Networks is possible according to national rules. This is an ERA-NET JPI-EC-AMR additional activity.

Note that JPIAMR Network calls do not fund research projects.

Scope of the call

Projects should aim to either:

Develop strategies, tools, technologies, and methods for the detection, monitoring, profiling and/or surveillance of antimicrobial resistance and dynamics leading to resistance.
Study ways to facilitate and implement the uptake and use of existing strategies, tools, technologies, and/or methods for the detection, monitoring, profiling and surveillance of antimicrobial resistance and dynamics leading to resistance.

Expected Outcomes

It is expected that this JPIAMR call will contribute to the urgent need to curb the burden associated with the most prioritised infections in different geographical settings. This topic area is also suitable to reinforce collaborations involving industry and social sciences. Regional LMIC led collaborations are welcomed. The results of the funded projects should contribute to improved understanding, monitoring and detection of AMR where efforts to curb AMR will have a global impact.

Suggested Focal Areas

Establish the validity of new or improved diagnostic tools, technologies and methods.
Evaluate how new or improved diagnostics can promote more prudent use of antibiotics (e.g. narrow spectrum antibiotics) in human and veterinary use
Rapid diagnostics (essential for optimal antimicrobial selection) and point-of-care techniques, to improve personalised or individual therapies
Development of new, or more efficient use and accessibility of already existing, tools, technologies and/or methods to detect AMR in multiple reservoirs, for example human, animal and environmental samples

Projects are encouraged to consider the global use of the tools, technologies and methods, including use in low and lower middle income settings (e.g. lack of laboratory facilities, affordable diagnostic tests, unreliable or unavailable electricity supplies or points-of-care-tests).

The following sub-topics are not within the scope of the call:

Investigations based on, or involving, clinical trials.
Investigations aiming to improve existing commercial technology or products (more details on this will be in the full call text and annexes)

Information & application

This call is closed.

Call text JPIAMR Network Plus (pdf 0,5 MB)

Funders

Canada
Canadian Institute of Health Research (CIHR)

France
French National Research Agency (ANR)

Italy
Ministry of Health (It-MOH)

Latvia
Ministry of Education and Science (IZM)

Norway
The Research Council of Norway (RCN)

Spain
National Institute of Health Carlos III (ISCIII)

Sweden
Swedish Research Council (SRC)

The Netherlands
The Netherlands Organisation for Health Research and Development (ZonMw)

Supported projects

Seven networks including 146 partners from 35 countries were funded within the JPIAMR 10th transnational call: “JPIAMR Network Plus 2020”. The total funding amount was approx. 737.000 €. Click on the network titles in the list below to read more on each network.

JPIAMR-VRI Network Call 2018

Related material

JPIAMR recognises a need to reinforce alignment of research. To promote this, the JPIAMR will establish a Virtual Research Institute in AMR (“the JPIAMR-VRI”) – a Global Network connecting research performing organisations, institutes, centres, and infrastructures. This Network call aims to identify research community needs and develop ideas to form the foundation for the JPIAMR-VRI.

The intent of the call is to form Networks of motivated groups to conceptualise and develop the JPIAMR-VRI. The Networks should identify research community needs, develop catalytic ideas and strategic plans to help bring the JPIAMR-VRI to Life!

Up to 21 Networks will be funded with up to 50,000 € each to connect experts from research performing organisations, institutes, centres and infrastructures and establish expertise clusters in the AMR community. Note that JPIAMR Network calls do not fund research projects.

Scope of the call

The JPIAMR-VRI will provide a platform to increase coordination, improve visibility of the AMR researcher base, facilitate knowledge exchange and capacity development across the globe, covering the full One Health spectrum.The JPIAMR-VRI is expected to:

Connect AMR researchers across the JPIAMR priority topics in a One Health approach
Build capacity and strengthen capability in AMR research
Facilitate access to scientific information and infrastructures
Bridge geographic borders in the research community through global reach
Break practical barriers between geographies and fields of research
Increase awareness and visibility of the issue of AMR and the importance of research in tackling this
Encourage the use of scientific evidence to inform policy and guideline makers

Expected Outcome

Applicants are invited to form JPIAMR Networks that are expected to provide plans to develop the JPIAMR-VRI.

Suggested focal areas

JPIAMR Networks may tackle one or more of the suggested focal areas below. These examples are neither mandatory nor limiting. Network tasks should address needs at a National and International level, include Low and Middle Income Country (LMIC) aspects and consider the One Health approach.

Examples of Network focal areas could include, but are not limited to:

Develop blueprints on: strategic focus, governance, funding/sustainability, infrastructure, engagement, implementation, the unique selling point of the JPIAMR-VRI, and/or addressing innovative “out of the box” ideas.
Develop a Communication and Knowledge Translation Strategy.
Develop a Partnerships Strategy to ensure key stakeholders, including industry and policy makers, and other networks are engaged and coordinate the alignment of other funded Networks.
Develop a Strategic Action Plan on Training to identify opportunities for capacity building and strengthen capability, with a focus on young investigators.
Develop a plan for a Global Platform for data sharing (e.g. clinical samples/data, scientific information and infrastructures including libraries or catalogues)
Develop a Map of other funded Networks (e.g. current information on expertise, fields of interest, demographics, available technologies and resources)

Information & application

This call is closed.

A startup workshop for all funded networks from the two transnational network calls launched by JPIAMR in 2018, JPIAMR Network Call on Surveillance and JPIAMR-VRI Network Call 2018, was organised in Amsterdam, The Netherlands in February 2019. The workshop report can be found here: Startup workshop report 2018 JPIAMR Transnational Networks.

Filmed interviews with the coordinators of the funded JPIAMR Networks can be found here: Discover the JPIAMR-VRI: Interviews with network coordinators February 2019

Funders

Canada
Canadian Institute of Health Research (CIHR)

Egypt
Academy of Scientific Research & Technology (ASRT)

France
French National Research Agency (ANR)

Germany
The Federal Ministry of Education and Research (BMBF)

Italy
Ministry of Health (It-MOH)

The Netherlands
The Netherlands Organisation for Health Research and Development (ZonMw)

Norway
The Research Council of Norway (RCN)

Spain
Instituto de Salud Carlos III

Sweden
Swedish Research Council (SRC)

United Kingdom
Medical Research Council (MRC)

Supported projects

Eight networks were funded within the JPIAMR 2018 call for transnational networks “Building the Foundation of the JPIAMR Virtual Research Institute.” Each funded network received €50,000 to establish expertise clusters to identify research community needs and develop ideas to form the foundation for the JPIAMR Virtual Research Institute (JPIAMR-VRI). Click on the network titles in the list below to learn more on each network.

Innovations against antibiotic-resistant bacteria: New targets, compounds and tools

The primary aim of the 6th joint call of the Joint Programming Initiative on Antimicrobial Resistance (JPIAMR) is to combine the resources, infrastructures, and research strengths of multiple countries in order to address the identification and validation of new targets, the development of new therapies, and new tools for new treatments (including new antibiotics).

The goal is to foster multinational research collaborations to add value to, and to build upon, the research conducted independently at national level, as well as to work together to develop new and urgently needed therapies.

The call will only cover research tackling the bacterial pathogens and the resistances identified in the Global priority list of antibiotic-resistant bacteria published by the WHO in September 2017 with the addition of multi- and extensively drug resistant Mycobacterium tuberculosis.

It is expected that through international collaborations combining complementary and synergistic research strengths, this JPIAMR call will contribute to the urgent need to curb the burden associated with the most prioritised infections. It is also a topic area suitable to reinforce academic – industry collaborations. The participation of industry is encouraged. The results of the funded projects should have an added value to society as a whole, the public health and finances by closing knowledge gaps and discovering new therapies. Although stand-alone projects are fully eligible, links with other European or international research programs and initiatives in the field will be of added value.

Information & application

This call is closed.

Funders

Belgium
The Research Foundation – Flanders (FWO)
Fund for Scientific Research-FNRS

Czech Republic
Ministry of Education, Youth and Sports

Egypt
Academy of Scientific Research and Technology- Egyptian Ministry of Higher Education and Scientific Research

Canada
Canadian Institute of Health Research (CIHR)

Finland
Academy of Finland

France
French National Research Agency (ANR)

Germany
The Federal Ministry of Education and Research (BMBF)

Ireland
Health Research Board

Israel
Chief Scientist Office, Ministry of Health

Italy
Ministry of Health

Latvia
State Education Development Agency

Norway
The Research Council of Norway (RCN)

Poland
National Science Centre

Romania
Ministry of Research and Innovation

Spain
Ministry of Economy, Industry and Competitiveness – State Research Agency
Instituto de Salud Carlos III

Sweden
Swedish Research Council (SRC)

Switzerland
Swiss National Science Foundation

Supported projects

Ten projects were awarded funding within the JPIAMR 6th transnational call: “Innovations against antibiotic-resistant bacteria: New targets, compounds and tools”. The total funding amount was 12,8 M€. Click on the project titles in the list below to learn more about each project.

Prevention and Intervention Strategies to control AMR infections

Call text Prevention and Intervention Strategies to control AMR infections (pdf 0,5 MB)

In order to protect and prolong the usefulness of existing antimicrobials, increasing cross-sectoral efforts are needed to rationalize their use and misuse in human and animal health and food production settings.

Key measures to achieve this are to improve existing and implement new evidence-based control, prevention, stewardship and intervention strategies to reduce the risk of acquisition, development and transmission of antibiotic-resistant bacteria and infection caused by these pathogens, in hospitalized patients, outpatients, healthy people, animals and the environment.

Despite significant investments in research and increased knowledge about the development, acquisition, occurrence, and transmission pathways of AMR, little of this research has translated into interventions to significantly improve health care by reducing improper antibiotic usage or infections by resistant microbes.

In summary, controlled integrated studies between human population, health care systems, and agricultural settings, multiple sectors are urgently needed to devise the optimal intervention strategies across diverse cultural settings and heterogeneous systems of human health and animal health and food production.

It is expected that through international collaborations that combine complementary and synergistic research strengths, this JPIAMR call will increase the understanding of prevention, control, stewardship and intervention strategies for AMR infections. Proposals are expected to clearly define targets and milestones to deliver relevant outcomes within the funding period.

Call Topics

The call will cover research addressing the following topics:

One Health oriented pilot studies to determine feasibility and protocols for future large scale multi-center and multi-national studies of different prevention or intervention strategies designed to prevent AMR infections in community, health care, agricultural and environmental settings. The One Health approach is encouraged, but not mandatory.
Compared effectiveness and economic evaluation of the implementation of new and/or more cost-effective methods for rapid detection and diagnosis of infections by multi-drug resistant microorganisms (MDR) for the purpose of identification of appropriate therapy, transmission routes or early detection of outbreaks in different settings.
Investigations of efficacy and effectiveness of behavioral intervention strategies, public awareness strategies or other stewardship strategies aiming at reducing the use and misuse of antibiotics and the development and transfer of AMR.
Assessment of new methods to improve and raise hygiene and sanitation standards to reduce infections in health and care settings.
Evaluation of the impact of new ways to standardize and utilize antimicrobial use and transmission data on intervention strategies and prevention of antimicrobial resistance.

Information & application

This call is closed.

Funders

Belgium
The Research Foundation – Flanders (FWO)

Canada
Canadian Institute of Health Research (CIHR)

Czech Republic
Ministry of Education, Youth and Sports (MEYS)

Germany
The Federal Ministry of Education and Research (BMBF)
Deutsches Zentrum für Luft- und Raumfahrt (DLR)

Ireland
Health Research Board (HRB)

Israel
Chief Scientist Office, Ministry of Health (CSO-MOH)

Italy
Ministry of Health (IT-MOH)

Latvia
Valsts izglītības attīstības aģentūra (VIAA)

The Netherlands
Zorgonderzoek Nederland (ZON)

Norway
The Research Council of Norway (RCN)

Poland
Narodowe Centrum Nauki (NCN)

Romania
National Authority for Scientific Research and Innovation (ANCSI)

Spain
Instituto de Salud Carlos III (ISCIII)

Sweden
Swedish Research Council (SRC)

Switzerland
Swiss National Science Foundation (SNSF)

Supported projects

Ten projects were awarded funding within the JPIAMR 5th transnational call: “Prevention and Intervention Strategies to control AMR infections”. The total funding amount was 11.5 M€. Click on the project titles in the list below to learn more about each project.

AMR Networks/Working groups

Related material

Call text AMR Networks/Working Groups 2016 (pdf 0,6 MB)

The call AMR Networks/Working groups sets out to assemble motivated groups of leading experts and establish Working Groups in order to enhance resource alignment and maximise existing and future efforts to combat AMR by pushing forward the conceptualisation of ideas.

The Working Groups will for example produce white papers, prospective views, guidelines, and/or best practice frameworks to identify key questions to be address or identify potential solutions to overcome barriers to antimicrobial resistance research studies.

Based on the priority topics identified in the JPIAMR Strategic Research Agenda, applicants are invited to tackle one or more of the suggested focal areas. Examples of questions within the areas are provided as a guide; however, those examples are neither mandatory nor limiting. Working Groups should be built with emphasise on what is needed at a National and International level to address AMR.

Suggested focal areas

Guidelines on use (Human & Veterinary) – Affordable stewardship
Surveillance in primary care
New anti-infective/ New adjuvant therapies / Alternative approaches
Evaluation of risk for generation of resistance in human setting
Rapid diagnostic tests
Role of environmental factors
Infrastructures/Biobanks available relevant to infection and AMR

Information & application

This call is closed.

A final workshop, Maximising Existing and Future Research Efforts and Resource Alignment to Combat AMR, was organised in Frankfurt am Main, Germany, in March 2018. The full workshop report can be downloaded here: Workshop report: Maximising Existing and Future Research Efforts and Resource Alignment to Combat AMR (pdf 1,2 MB)

Filmed interviews with coordinators of some of the funded JPIAMR Networks can be found here: Results from the 4th JPIAMR Joint Call “AMR Networks/Working Groups”: Interviews with network coordinators March 2018

Funders

Belgium
The Research Foundation – Flanders (FWO)

Canada
Canadian Institute of Health Research (CIHR)

France
French National Research Agency (ANR)

Germany
The Federal Ministry of Education and Research (BMBF)

The Netherlands
The Netherlands Organisation for Health Research and Development (ZonMw)

Norway
The Research Council of Norway (RCN)

Spain
Instituto de Salud Carlos III

Sweden
Swedish Research Council (SRC)

United Kingdom
Medical Research Council (MRC)

Supported projects

Thirteen networks with approximately 160 partners were funded within the 4th JPIAMR Joint Call “AMR Networks/Working Groups”. Each funded network received approximately €50,000 to work on the development of different AMR policy recommendations and research strategies. Click on the network titles in the list below to learn more on each network.

Antimicrobial Resistance through the JPIAMR

New therapeutic approaches are urgently needed to control bacterial infections and safeguard the health of populations. The reviving of ND-AB and research on improving the efficiency of antibiotics by using them in combination with another antibiotics or a nonantibiotic can be a fast solution to overcome antimicrobial resistance.

The primary aim of this second joint call of JPIAMR is to combine the resources, infrastructures, and research strengths of multiple countries in order to overcome antibiotic resistance. The goal is to foster multinational translational research collaborations that can accomplish more than individual countries working independently, and improve the control of bacterial infections.

Call Topics

Sustain defense against AMR in human and animal health to reduce occurrence of resistance or overcome established resistance by:

reviving Neglected and Disused AntiBiotics (ND-AB)
designing combinations of ND-AB and antibiotic
designing combinations of ND-AB and non-antibiotic

The activity of ND-AB and the synergy of the combinations of ND-AB with other antibiotics and non-antibiotic should be validated by testing for activity/synergy in vitro and in validated animal models with pharmacokinetic/pharmacodynamic (PK/PD) modelling.

Information & application

This call is closed.

Call text Antimicrobial Resistance through the JPIAMR 2015 (pdf 0,6 MB)

Funders

Argentina
Ministry of Science, Technology and Productive Innovation (MINCYT)

Belgium
The Research Foundation – Flanders (FWO)
The National Fund for Scientific Research – French speaking community (FNRS)

France
French National Research Agency (ANR)

Germany
The Federal Ministry of Education and Research (BMBF)

Italy
The Ministry of Health (MoH)

The Netherlands
The Netherlands Organisation for Health Research and Development (ZonMw)

Norway
The Research Council of Norway (RCN)

Poland
National Centre for Research and Development (NCBR)

Sweden
Swedish Research Council (SRC)

Supported projects

Three projects were awarded funding within the second JPIAMR Joint Call “Antimicrobial Resistance through the JPIAMR”. Click on the project titles in the list below to learn more about each project.

InnovaResistance: Innovative approaches to address antibacterial resistance

Related material