Nine New JPIAMR SAB members

JPIAMR is pleased to welcome nine new members to the Scientific Advisory Board, SAB. The new members have diverse experience in the field of AMR, adding key knowledge and experiences to the whole SAB. Now fifthteen members strong.

The following SAB members have been appointed by the JPIAMR Management Board for the period 2019-2021:

  • Till Bachmann, UK
  • Rafael Cantón, Spain
  • Ramanan Laxminarayan, USA and India
  • Marc Lemonnier, France
  • Luísa Vieira Peixe, Portugal
  • Anngret Schneider, Germany
  • Constance Schultsz, Netherlands
  • Ed Topp, Canada
  • Jordi Vila, Spain

For individual biographies and further information, please click here.

Kick-off: ECRAID, the European Clinical Research Alliance on Infectious Diseases

JPIAMR will be participating in a high-level meeting in Brussels, on January 17th 2019, on the development of ECRAID, the European Clinical Research Alliance on Infectious Diseases. ECRAID envisages a European-wide sustainable clinical research organization for infectious diseases and AMR, antimicrobial resistance. Laura Marin, JPIAMR Head of Secretariat, will participate in panels, etc.

ECRAID’s vision is to create a coordinated and permanent European clinical research infrastructure for clinical research on infectious diseases.  The focus is on two major challenges: emerging infectious diseases with epidemic or pandemic potential, caused by new or re-emerging pathogens, and AMR (antimicrobial resistance). ECRAID will be enable clinical research to be faster and easier having rapid access to and knowledge of developed clinical and laboratory sites. Trials will be conducted continuously to expand on knowledge and experience.

The organisations aim is to protect public health by generating evidence in order to improve diagnosis, prevention, and treatment.  The ECRAID mission is to facilitate and develop world class research to protect citizens of Europe against AMR (antimicrobial resistance) and infectious diseases, over the long term. Professor Herman Goossens together with epidemiologist Marc Bonten, is the project coordinators of ECRAID.

There will be panel discussions with clinical research networks, preclinical research networks, pharmaceutical and diagnostic companies,
SMEs, etc. Together with speakers such as EU Commissioner Carlos Moedas, Herman Goossens, Marc Bonten, Magda Chlebus, Executive Director, Science Policy & Regulatory Affairs, EFPIA and Jeremy Farrar, Director of the Wellcome Trust, and others. This is a closed meeting.

One Health in Focus when EU-JAMRAI Interviews JPIAMRs Laura Marin

In the latest newsletter form EU-JAMRAI, Laura Marin, JPIAMRs Head of Secretariat, is interviewed. The topic is international AMR initiatives and the need of a One Health Approach.

This fits well with JPIAMR’s focus. Our Strategic Research and Innovation Agenda is based on a One Health approach, and the initiatives created by JPIAMR is often centered on global collaboration and coordinating public AMR funding.

The interview was made earlier this year at ECCMID in Spain.

Now Open: Call on AMR Diagnostics and Surveillance

The Call on Diagnostics and Surveillance 2019 will fund joint transnational research projects addressing the development of diagnostic and surveillance tools, technologies and methods to detect antimicrobial resistance (AMR). Projects should address the diagnosis of AMR infections in clinical and veterinary settings, or the surveillance of AMR in humans, animals and the environment. The call promotes projects with impact in low and middle income countries (LMICs) in Asia and Africa.

AMR has become one of the major global health and development challenges of the 21st century. The threat of AMR is particularly high in resource-limited and high-risk settings. This is linked to issues such as weak human and animal health systems; diverse means of food production, processing and consumption; food safety and food security; water, hygiene and sanitation challenges; and the global movement of people and goods.

In response to these challenges, the JPIAMR is pleased to launch this joint transnational call for proposals for innovative research projects on new or improved diagnostic and surveillance strategies, tools, technologies and methods.  The call will support research projects that also have the potential for impact in areas where the risk and burden of AMR is greatest, such as in LMIC settings in Asia and Africa. Projects are encouraged to use a One Health approach where relevant.

The total call budget is approx. 20 million Euro.

For full information about the call and the application process, please visit the call page.

The two-step application process (pre-proposal, full proposal) will have the following targeted timetable:

November 15 2018Preannouncement: Antibiotic Awareness Day 2018
December 5 2018Publication of the JPIAMR ERA-NET 2019 Call
February 18 2019 (11:00 CET)Submission deadline for pre-proposals
Mid April 2019Full proposal invitations sent to project coordinators
June 17th 2019 (11:00 CET)Submission deadline for full proposals
Last week September 2019Final funding decision taken by the CSC
Mid October 2019Final funding decision announced to applicants
End of 2019/Early 2020Start of funding

Pre-announcement: Call on AMR Diagnostics and Surveillance

JPIAMR is pleased to pre-announce a joint transnational research call for proposals for innovative research projects on new or improved diagnostic and surveillance strategies, tools, technologies and methods.  The call will support research projects that also have the potential for impact in areas where the risk and burden of AMR is greatest, such as in LMIC settings in Asia and Africa. Projects are encouraged to use a One Health approach where relevant.

The projected call budget is approx. 20 million Euro.

To read more about the call, please click here.

JPIAMR Highlighted in G20 Health Ministers Joint Declaration

The 2018 G20 Health Ministerial Meeting in Mar del Plata, Argentina, concluded on October 4th with a joint declaration on concrete health policy proposals.

The document considers health a key aspect for sustainable development and calls for a further strengthening health systems. It also recommends concrete actions to address global issues such as antimicrobial resistance, and with commitments for “increasing the level of awareness on the prudent and responsible use and disposal of antibiotics of all healthcare providers, veterinarians, farmers and food producers and of the general public.”

In the declaration, the G20 also mentions JPIAMR together with GARDP, UNITAD, CARB-X and the TB-Alliance, welcoming the work of these leading international initiatives.

Please view the full declaration here.

Open consultation: JPIAMR is updating the Strategic Research and Innovation Agenda (SRIA)

Update of the JPIAMR Strategic Research and Innovation Agenda 2018

The JPIAMR recognises that innovation is critically important in the field of AMR, as there is a strong need of new therapeutics, diagnostics, and innovative infection prevention and intervention measures. The JPIAMR is therefore currently refreshing its JPIAMR Strategic Research Agenda (SRA) to take account of recent research findings and to extend the JPIAMR SRA into a Strategic Research and Innovation Agenda (SRIA).

The research objectives and research priorities of the JPIAMR SRIA are now open for public consultation. We welcome feedback on the research topics from the AMR community from the 9th of July to the 15th of September (12.00 CET).

For more information and instructions for providing feedback, please click here.

Fourth JPIAMR Network Call Workshop – report and interviews

In March researchers gathered in Frankfurt am Main in a final workshop, Maximising Existing and Future Research Efforts and Resource Alignment to Combat AMR, to share some of their activities and findings from research that was supported by funding within the JPIAMR call for networks. Here we present the full workshop report and filmed interviews with some of the funded networks.

The fourth JPIAMR call for networks closed on June 6, 2016. Participating countries in the network call were JPIAMR members: France, Canada, Belgium Spain, the United Kingdom, Germany, Norway, Sweden, and the Netherlands. The coordinators from the countries participating in the call created networks of researchers from many different countries and fields of research.

Major Conclusions

  • The Network funding mechanism facilitated the formation of successful networks in all strategic JPIAMR areas.
  • JPIAMR Network funding allowed Networks to carry out a broad range of activities with different outcomes, including white papers/position papers, conferences/workshops, systematic reviews, Standard Operating Procedures, online courses, guidance documents and journal articles, amongst others.

JPIAMR has the One Health approach as an integral part of the Strategic Research Agenda. This is one of the key strengths of JPIAMR and it is reflected in the diversity of the network topics.

The full workshop report can be downloaded here.

About the participating networks

The assembled networks had emphasis on needs at a National and International level to address AMR, within these areas:

  • Guidelines on use (Human & Veterinary) – Affordable stewardship
  • Surveillance in primary care
  • New anti-infective/ New adjuvant therapies / Alternative approaches
  • Evaluation of risk for generation of resistance in human setting
  • Rapid diagnostic tests
  • Role of environmental factors
  • Infrastructures/Biobanks available relevant to infection and AMR

The networks spanned all of the JPIAMR pillars and were mostly multidisciplinary (spanning at least two pillars). A range of sizes of the networks were represented at the workshop.

Interviews with coordinators of some funded JPIAMR Networks

Research Network: Flies (Diptera: Muscidae) and the Spread of Antimicrobial Resistant Bacteria

Research Network: INFACT – AMR and Intensive Care Units

Research Network: Rapid Diagnostics

Research Network: AMR Stewardship in Hospitals – What Works?

Report – Countries Should Increase Funding for AMR Research by 50%

Today we are reached by the final report from DRIVE-AB with the headline: “Revitalizing the Antibiotic Pipeline“. The context is that “The current pipeline for innovative antibiotics in various stages of R&D is insufficient, potentially delivering no more than one innovative antibiotic for a “critical” World Health Organization (WHO) priority pathogen within the next five years.”, the report say in the beginning.  A key reason for the DRIVE-AB report is to bring recommendations and guidance in the present context, when we are facing increased antibiotic resistance on a global scale.

One of the main recommendations is that countries should increase funding for AMR.

“Countries should make long-term commitments to continue financing of antibacterial R&D and ideally increase push funding by about 50 per cent.”, states the report.

DRIVE-AB finds that: “There may be capacity within existing multinational grant funding agencies – e.g. CARB-X, GARDP, JPIAMR (Joint Programming Initiative on Antimicrobial Resistance) – to absorb and effectively deploy more capital.”

So, we are happy to see that JPIAMR is acknowledged as a key organisation and vehicle, among others,  who are trusted with the mission to fund even more research in order to harness AMR on a global scale. Since JPIAMR is coordinating research and funding for it’s 26 member nations – it fits very well to expand the operations in this direction.

The Drive-AB report continues: “Owing to the existing pipeline, much of this immediate funding should be placed in early- and mid-stage grants until the pipeline becomes more robust. Granting agencies should have specific calls for research targeting pathogens that pose the most urgent public health threats (e.g. WHO’s priority pathogens list for the discovery phase and TPPs for the development phase).”

The ongoing JPIAMR call for “New targets, compounds and tools – innovating against antibiotic resistant bacteria“, is a perfect example how countries are pooling resources and research to collaborate. This call responds to WHOs list of priority pathogens just as the report recommends.

However, funding is linked with the ability to both reach and enable researcher to apply for funds. This is something many more entities in the AMR field could collaborate on to a greater extent. If researchers are not aware of available funds and contexts to support research, we may miss opportunities to support research that can be life changing for the many.

The 6th Transnational Call is Now Open

The sixth transnational call for research projects for the JPIAMR within the ERA-NET JPI-EC-AMR

THE CALL IS OPEN

The JPIAMR, in partnership with sixteen member countries; Belgium, Czech Republic, Egypt, Finland, France, Germany, Ireland, Israel, Italy, Latvia, Norway, Poland, Romania, Spain, Sweden and Switzerland, is launching a sixth joint call for transnational research projects. The total budget of the 6th Call is approx. 14.4 million Euro.

The call targets research in the following topic:

Innovations against antibiotic-resistant bacteria: new targets, compounds and tools. Fundamental, translational research, with the exception of clinical trials.

Call procedure

The 6th Call has a two-step procedure. With a first stage, a pre-proposal submission, from which selected applicants will be invited to submit a full proposal, the second stage. The final funding decision will be announced in October / November 2018.

Deadlines

The pre-proposal submission deadline is March 7, 2018, (17:00, CET).
The full proposal submission deadline is June 14, 2018, (17.00, CET).

Information and application

For more detailed information and links to application process, please visit the page about the 6th Call.

6th Call Secretariat and National Points of Contact

The 6th Call Secretariat is hosted by the French National Research Agency, ANR.

All questions on national rules, eligibility, etc. should be directed to the national contacts, for contact information please visit the page about the 6th Call.

Spread the News

Reach out to researchers in participating countries. Use the template below and link to the page about the 6th call.