Northern lights

Disrupting drug resistance using innovative design

Pre-announcement: In 2022, JPIAMR will launch an international call for projects under the umbrella of the JPIAMR and within the framework of the ERA-NET JPIAMR-ACTION. The call Disrupting drug resistance using innovative design will involve 26 funding organisations from 17 countries. The total estimated call budget is 17 million Euro.

Call picture Disrupting drug Resistance Using Innovative Design: Northern lights over a fjord. Silhouette of mountains in the background.

In line with the JPIAMR Strategic Research and Innovation Agenda, this call will focus on tackling the rising threat of antimicrobial resistance. Declining effectiveness of existing antimicrobials together with the low and insufficient number of promising new antimicrobials in the pipeline stresses the urgency to develop new protocols and innovative approaches for effective delivery and use of the already existing antimicrobials. This call aims to improve the treatment of bacterial and fungal infections (including co-infection) and/or the prevention of the emergence/spread of resistance in humans, animals or plants through the improvement of the efficacy, specificity, delivery, combinations and/or repurposing of drugs and plant protection agents.

Through this call, the ERA-NET JPIAMR-ACTION intends to create and reinforce the collaboration between research partners coming from different countries and different fields of expertise to promote research on antimicrobial resistance.

Please note that the information provided in the pre-announcement is not binding and that changes may occur without notice until the call opening in January 2022.

Topic of the call

Proposals should focus on licenced antimicrobial agents (antibiotics/antifungals) or agents under pre-clinical and/or early clinical development, and should address at least one of the following topics:

  • Improvement of drug/plant protection agent efficacy and/or specificity through chemical modifications (including hit to lead optimisation)
  • Drug/plant protection agent repurposing;
  • Optimisation of drug/plant protection agent combinations, alone or with adjunct therapies (including therapeutic vaccines);
  • Design and implementation of new strategies (including optimisation of drug doses) for improved application, efficacy and delivery of single or combinations of antimicrobials;
  • Design and implementation of innovative tools, including novel chemistry and/or new materials for improved application, efficacy and delivery of antimicrobials.

Proposals can focus on one or more of the three “One-Health” settings, namely:

  • Human Health, and/or
  • Animal Health (including wildlife, livestock, fishes, and companion animals), and/or
  • Plants (including trees and crops)

The following sub-topics are out of scope of the call:
• Antiviral and antiparasitic agents
• Discovery and/or screening of new compounds, new vaccines and/or new targets
• Proposals solely aiming to develop new diagnostics or new companion diagnostics (companion diagnostics in evaluation of the antimicrobials can be examined but they should not be the main topic of the proposal.)

Participation of end-users, stakeholders and companies is encouraged.

Eligibility

Consortia should consists of a maximum of six (6) project partners (including non-funded partners). The maximum number of partners can be increased to seven (7) if the consortium includes a company, or a partner coming from low or middle income countries, Lithuania or Poland. The budget of non-funded partners shall not exceed 30% of the total transnational project budget requested. Furthermore, consortia should always consist of a majority of project partners eligible for funding. Funding is granted for a maximum of three (3) years in accordance with national regulations and applicable legal provisions.

Timeline

The call Disrupting drug resistance using innovative design will follow a two-step evaluation procedure.

11 January 2022 – Call opens

8 March 2022 (14.00 CET) – Deadline pre-proposals

5 July 2022 – Deadline full proposals

Information & application

The full call text and the link to the digital submission platform will be published when the call opens in January.

Webinar for applicants

A live webinar will be organised on the 25th of January 2022. This webinar will present the call and the partner search tool. Representatives from funders participating in the call will answer questions live.

Partner Search Tool

A match-making tool will be created for applicants, to facilitate networking and the creation of consortia.

The tool can be consulted for several purposes:

  • Partner looking for project: As individual researcher or a representative of a lab or research team, searching for a project to join.
  • Project looking for partner: If you want to build a consortium around an existing project and want to find partners for your project ideas.

The tool will open on the day of the launch of the call.

Funders

Partners working in eligible low and middle income countries can be funded by the Swedish International Development Cooperation Agency (Sida).

Belgium
Fonds voor Wetenschappelijk onderzoek-Vlaanderen (FWO)
Fonds de la Recherche Scientifique (FNRS)

Canada
Canadian Institute of Health Research (CIHR)

Czech Republic
Ministry of Education, Youth and Sports (MEYS)

Estonia
Estonian Research Council (ETAg)

France
Agence Nationale de la Recherche (ANR)

Germany
The Federal Ministry of Education and Research (BMBF)

Hungary
National Research, Development and Innovation Office (NKFIH)

Israel
Ministry of Health (CSO-MOH)

Italy
Fondazione Regionale per la Ricerca Biomedica (FRRB)
Ministero della Salute (It-MoH)

Latvia
Valsts Izglitibas Attistibas Agentura (VIAA)
Latvijas Zinatnes padome (LZP)

Lithuania
Research Council of Lithuania (RCL)

Moldova
Agentia Nationala Pentru Cercetare Si Dezvoltare (ANCD)

Poland
Narodowe Centrum Nauki (NCN)
National Centre for Research and Development (NCBR)

Spain
Agencia Estatal de Investgacion (AEI)
Instituto de Salud Carlos III (ISCIII)

Sweden
Swedish Research Council (SRC)
Swedish International Development Cooperation Agency (Sida)
Vinnova, Sweden’s innovation agency

Switzerland
Swiss National Science Foundation (SNSF)

United Kingdom
Medical Research Council (MRC)
Biotechnology and Biological Sciences Research Council (BBSRC)
Engineering and Physical Sciences Research Council (EPSRC)

Supported projects

Shadows of people on a colourful background.

Diagnostics and Surveillance Networks

Pre-announcement: JPIAMR will launch in 2022 a transnational network call under the umbrella of the JPIAMR and within the framework of the ERA-NET JPIAMR-ACTION. The call Diagnostics and Surveillance Networks involves funding organisations from 11 countries to date. Networks can be funded with a maximum of 50,000 Euro each.

Call picture Diagnostics and Surveillance Networks 2022. Shadows of people on a colourful background.

The aim of this call is to assemble networks of leading experts and stakeholders with an intent to facilitate the development, optimisation and use of diagnostic and surveillance tools, technologies and systems. Networks should work towards the conceptualisation of ideas in order to provide white papers, guidance documents and/or best practices/roadmaps and evidence frameworks to identify key questions to be addressed and/or potential solutions to overcome barriers to enhanced surveillance and advanced diagnostics to reduce the burden of AMR.

Eleven (11) JPIAMR-ACTION members are participating in this network call to date. Each network coordinator will be able to apply for a maximum of 50,000 Euro for 12 or 24 months period for support of its activities.

The call opens in April 2022.

Information & application

The full call text and the link to the online submission platform will be published when the call opens.

Timeline

22 March 2022 – Detailed pre-announcement text available

12 April 2022 – Call opens

28 April 2022 – Webinar for applicants

14 June 2022 – Proposal deadline

Funders

Egypt
The Academy of Scientific Research and Technology (ASRT)

Estonia
Estonian Research Council (ETAg)

France
Agence Nationale de la Recherche (ANR)

Italy
Ministero della Salute (It-MoH)

Lithuania
Research Council of Lithuania (RCL)

Moldova
Agentia Nationala Pentru Cercetare Si Dezvoltare (ANCD)

Netherlands
Zorgonderzoek Nederland Zon (ZonMw)

Norway
Research Council of Norway (RCN)

Spain
Instituto de Salud Carlos III (ISCIII)

Sweden
Swedish Research Council (SRC)

United Kingdom
Medical Research Council (UKRI/MRC)

Supported projects