Inhibition of antimicrobial drug resistance: Exploiting an old drug as a basis for inhibitory discovery (EXPLOIT)

Antimicrobial resistance (AMR) is a serious emerging threat for patients and the healthcare systems. It has been anticipated by the Institute and Faculty of Actuaries in Britain that AMR has the potential to reduce Gross Domestic Product (GDP) by 3.5% globally and to kill an additional 10 million people by 2050, and as such the topic is of high importance to the public.

Completed project

Our working group will highlight the efforts made in the field by academics and industry alike and raise awareness on the urgency of action and proposes the use of an old nitrofuran drug for future development of potent antimicrobials by intense study of its use, potency, and the fundamental science behind its mode of action and resistance mechanisms. The inclusion of distinguished and prominent scientists in the field coming from different backgrounds will emphasize a multidisciplinary effort is needed to tackle the serious problem of AMR in a timely fashion.

 

Network partners

  • Klaas Martinus Pos, Goethe University Frankfurt, Germany (Coordinator)

This network includes 10 partners, please click on the following link to see complete network composition: Network composition Inhibition of antimicrobial drug resistance: Exploiting an old drug as a basis for inhibitory discovery (EXPLOIT)

 

Publications