PHARMASEA integrates international expertise to answer key research questions on fate and biological effects of active pharmaceutical ingredients (APIs), well recognized contaminants of emerging concern (CECs) for marine ecosystems.
The project will allow in-depth studies on APIs distribution, effects and risks in four European coastal areas, targeting (1) occurrence, uptake and trophic transfer along regional marine food webs; (2) bioaccumulation/excretion kinetics, potential ecotoxicological effects from molecular to individual levels, and characterization of modes-of-action in model and selected marine species; (3) development of specific risk assessment procedures for APIs.
The communication and connection with industries, private and public stakeholders as well as citizen engagement are important aims to promote public awareness, pre-normative research and implementation into European Directives. The project is expected to have a major impact enhancing the scientific knowledge and awareness on interactions between human and environmental health. The results could influence prescribing and disposal practices of domestic medicines and increase market opportunities and competitiveness of European pharma industries investing on environmental sustainability of their products.
- Francesco Regoli, Polytechnic University of Marche, Italy (Coordinator)
- Thomas Braunbeck, University of Heidelberg, Germany
- Daniela Maria Pampanin, University of Stavang, Norway
- Purificación López Mahía, Universidade da Coruña (UDC), Spain
- Víctor M. León, Spanish Institute of Oceanography, Spain