JPIAMR Network Call on Surveillance

The overarching goal of JPIAMR research on Surveillance is to standardise, improve and extend surveillance systems on antibiotic use and on AMR in humans, animals, food, and the larger environment. Surveillance is a pre-requisite for assessing the success of AMR stewardship measures, infection prevention and control, and the effectiveness of new therapeutic and diagnostic options.

In this network call JPIAMR will support networks of leading experts with the aim to enhance resource alignment and maximize existing and future efforts to combat AMR by pushing forward the conceptualisation of new ideas with the field of AMR Surveillance.

Up to 21 networks will be funded with up to 50 000 € each under this call. Note that the JPIAMR network calls do not fund research projects.

Scope of the call

Surveillance networks are essential to monitor the threat of AMR and guide public health policy. In order to understand antibiotic resistance, we must understand whether resistance genes are highly mobile and whether dominant pathogenic clones spread resistance globally. However, countries have different levels and methods of surveillance and many lack national reporting systems leading to major gaps in AMR surveillance and an urgent need to strengthen collaboration on global AMR surveillance.

The WHO GLASS Initiative is the first global collaborative effort to standardise AMR surveillance. GLASS is now working towards the integration of other surveillance initiatives on antimicrobial consumption and AMR in the food chain but surveillance activities that include data collection on the prevalence of antibiotic-resistant bacteria among healthy individuals and animals are also needed.

Applicants are invited to form JPIAMR networks that are expected to provide white papers, prospective views, guidelines and/or best practice/roadmap/systematic reviews and frameworks to identify key questions to be addressed or identify potential solutions to overcome barriers for AMR surveillance and the implementation of surveillance research studies.
JPIAMR networks may tackle one or more of the suggested focal areas below. However, these examples are neither mandatory nor limiting. Networks should address needs at a National and International level and encourage to include Low Middle Income Country (LMIC) aspects.

  1. Impact of surveillance on prevention, intervention, clinical practice, infection control, treatment and patient management.
  2. Surveillance of AMR in the healthy population: Risk factors; risk groups (e.g. migrants, travelers), reservoirs, and monitoring systems.
  3. Surveillance of non-human AMR reservoirs: Strategies, models, and technologies for tracing AMR in food, animals and the environment.
  4. Improvement and standardisation of methods.
  5. Quality assurance, curation and sharing data.
  6. Surveillance technology and tools: Optimization of methods for outbreaks, rapidly emerging clones, resource-poor settings and global coverage.
  7. Social networks, big data and deep learning for AMR surveillance and prevention.

Not within the Scope of the call

Networks are not expected to duplicate or create new open access systems (e.g. ECDC atlas, GLASS, European Health Information Gateway of WHO/Europe). It is important that the networks within the call are well-informed about ongoing activities in EC/ECDC, WHO, FAO, OIE. Research projects are not supported.

Information & application

This call is closed.

A startup workshop for all funded networks from the two transnational network calls launched by JPIAMR in 2018, JPIAMR Network Call on Surveillance and JPIAMR-VRI Network Call 2018, was organised in Amsterdam, The Netherlands in February 2019. The workshop report can be found here: Startup workshop report 2018 JPIAMR Transnational Networks.

Filmed interviews with some of the coordinators of the funded JPIAMR Networks can be found here: Discover the JPIAMR surveillance networks: Interviews with network coordinators February 2019

Funders

Belgium
The Research Foundation – Flanders (FWO)

France
French National Research Agency (ANR)

Germany
The Federal Ministry of Education and Research (BMBF)

Ireland
Health Research Board (HRB)

Italy
Italian Ministry of Health

The Netherlands
The Netherlands Organisation for Health Research and Development (ZonMw)

Norway
The Research Council of Norway (RCN)

Spain
Instituto de Salud Carlos III

Sweden
Swedish Research Council (SRC)

United Kingdom
Medical Research Council (MRC)

Supported projects

Ten networks were awarded funding within the JPIAMR 7th transnational call: “2018 Network Call on Surveillance”. Each funded network received €50,000 to enhance resource alignment and efforts in the field of AMR surveillance. Click on the network titles in the list below to learn more on each network.

Prevention and Intervention Strategies to control AMR infections

In order to protect and prolong the usefulness of existing antimicrobials, increasing cross-sectoral efforts are needed to rationalize their use and misuse in human and animal health and food production settings.

Key measures to achieve this are to improve existing and implement new evidence-based control, prevention, stewardship and intervention strategies to reduce the risk of acquisition, development and transmission of antibiotic-resistant bacteria and infection caused by these pathogens, in hospitalized patients, outpatients, healthy people, animals and the environment.

Despite significant investments in research and increased knowledge about the development, acquisition, occurrence, and transmission pathways of AMR, little of this research has translated into interventions to significantly improve health care by reducing improper antibiotic usage or infections by resistant microbes.

In summary, controlled integrated studies between human population, health care systems, and agricultural settings, multiple sectors are urgently needed to devise the optimal intervention strategies across diverse cultural settings and heterogeneous systems of human health and animal health and food production.

It is expected that through international collaborations that combine complementary and synergistic research strengths, this JPIAMR call will increase the understanding of prevention, control, stewardship and intervention strategies for AMR infections. Proposals are expected to clearly define targets and milestones to deliver relevant outcomes within the funding period.

Call Topics

The call will cover research addressing the following topics:

  • One Health oriented pilot studies to determine feasibility and protocols for future large scale multi-center and multi-national studies of different prevention or intervention strategies designed to prevent AMR infections in community, health care, agricultural and environmental settings. The One Health approach is encouraged, but not mandatory.
  • Compared effectiveness and economic evaluation of the implementation of new and/or more cost-effective methods for rapid detection and diagnosis of infections by multi-drug resistant microorganisms (MDR) for the purpose of identification of appropriate therapy, transmission routes or early detection of outbreaks in different settings.
  • Investigations of efficacy and effectiveness of behavioral intervention strategies, public awareness strategies or other stewardship strategies aiming at reducing the use and misuse of antibiotics and the development and transfer of AMR.
  • Assessment of new methods to improve and raise hygiene and sanitation standards to reduce infections in health and care settings.
  • Evaluation of the impact of new ways to standardize and utilize antimicrobial use and transmission data on intervention strategies and prevention of antimicrobial resistance.

Information & application

This call is closed.

Call text Prevention and Intervention Strategies to control AMR infections (pdf 0,5 MB)

Funders

Belgium
The Research Foundation – Flanders (FWO)

Canada
Canadian Institute of Health Research (CIHR)

Czech Republic
Ministry of Education, Youth and Sports (MEYS)

Germany
The Federal Ministry of Education and Research (BMBF)
Deutsches Zentrum für Luft- und Raumfahrt (DLR)

Ireland
Health Research Board (HRB)

Israel
Chief Scientist Office, Ministry of Health (CSO-MOH)

Italy
Ministry of Health (IT-MOH)

Latvia
Valsts izglītības attīstības aģentūra (VIAA)

The Netherlands
Zorgonderzoek Nederland (ZON)

Norway
The Research Council of Norway (RCN)

Poland
Narodowe Centrum Nauki (NCN)

Romania
National Authority for Scientific Research and Innovation (ANCSI)

Spain
Instituto de Salud Carlos III (ISCIII)

Sweden
Swedish Research Council (SRC)

Switzerland
Swiss National Science Foundation (SNSF)

Supported projects

Ten projects were awarded funding within the JPIAMR 5th transnational call: “Prevention and Intervention Strategies to control AMR infections”. The total funding amount was 11.5 M€. Click on the project titles in the list below to learn more about each project.

AMR Networks/Working groups

The call AMR Networks/Working groups sets out to assemble motivated groups of leading experts and establish Working Groups in order to enhance resource alignment and maximise existing and future efforts to combat AMR by pushing forward the conceptualisation of ideas.

The Working Groups will for example produce white papers, prospective views, guidelines, and/or best practice frameworks to identify key questions to be address or identify potential solutions to overcome barriers to antimicrobial resistance research studies.

Based on the priority topics identified in the JPIAMR Strategic Research Agenda, applicants are invited to tackle one or more of the suggested focal areas. Examples of questions within the areas are provided as a guide; however, those examples are neither mandatory nor limiting. Working Groups should be built with emphasise on what is needed at a National and International level to address AMR.

Suggested focal areas

  • Guidelines on use (Human & Veterinary) – Affordable stewardship
  • Surveillance in primary care
  • New anti-infective/ New adjuvant therapies / Alternative approaches
  • Evaluation of risk for generation of resistance in human setting
  • Rapid diagnostic tests
  • Role of environmental factors
  • Infrastructures/Biobanks available relevant to infection and AMR

Information & application

This call is closed.

Call text AMR Networks/Working Groups 2016 (pdf 0,6 MB)

A final workshop, Maximising Existing and Future Research Efforts and Resource Alignment to Combat AMR, was organised in Frankfurt am Main, Germany, in March 2018. The full workshop report can be downloaded here: Workshop report: Maximising Existing and Future Research Efforts and Resource Alignment to Combat AMR (pdf 1,2 MB)

Filmed interviews with coordinators of some of the funded JPIAMR Networks can be found here: Results from the 4th JPIAMR Joint Call “AMR Networks/Working Groups”: Interviews with network coordinators March 2018

Funders

Belgium
The Research Foundation – Flanders (FWO)

Canada
Canadian Institute of Health Research (CIHR)

France
French National Research Agency (ANR)

Germany
The Federal Ministry of Education and Research (BMBF)

The Netherlands
The Netherlands Organisation for Health Research and Development (ZonMw)

Norway
The Research Council of Norway (RCN)

Spain
Instituto de Salud Carlos III

Sweden
Swedish Research Council (SRC)

United Kingdom
Medical Research Council (MRC)

Supported projects

Thirteen networks with approximately 160 partners were funded within the 4th JPIAMR Joint Call “AMR Networks/Working Groups”. Each funded network received approximately €50,000 to work on the development of different AMR policy recommendations and research strategies. Click on the network titles in the list below to learn more on each network.

Transmission dynamics 2016 call picture

AMR Transmission Dynamics

The primary aim of the third joint call of JPIAMR, AMR Transmission Dynamics, is to combine the resources, infrastructures, and research strengths of multiple countries in order to address transmission of antibiotic resistance following a One Health approach.

The goal is to foster multinational research collaborations to add value to and to build upon the research conducted independently at national level and to work together to improve the control of resistant bacterial infections of clinical and/or veterinary importance only. The total funding for this call is over 24 million euro with a 6 million euro European Commission “topping up” fund.

Call Topics

To understand the acquisition, persistence/ retention, and transmission of resistant organisms and resistance genes, research should investigate:

  • Selection of resistance and its transmission between individuals and between human and non-human sources
  • The success of clones, organisms, and resistance patterns and the role of different genetic elements.
  • The fitness of the resistant bacteria in clinical, community, veterinary, and environmental settings.

Information & application

This call is closed.

Call text AMR Transmission Dynamics (pdf 0,8 MB)

Funders

The call budget for this call is over 24 million Euro from all participating countries plus an additional 6 million euro contribution from the European Commission.

Belgium
The Research Foundation – Flanders (FWO)
The National Fund for Scientific Research – French speaking community (FNRS)

Canada
Canadian Institute of Health Research (CIHR)

Denmark
The Danish Council for Strategic Research

France
French National Research Agency (ANR)

Germany
The Federal Ministry of Education and Research (BMBF)

Israel
Chief Scientist Office, Ministry of Health (CSO-MOH)

Italy
The Ministry of Health (MoH)

Latvia
State Education Development Agency (VIAA )

The Netherlands
The Netherlands Organisation for Health Research and Development (ZonMw)

Norway
The Research Council of Norway (RCN)

Poland
National Centre for Research and Development (NCBR)

Portugal
National funding agency for science, research and technology (NCBR)

Romania
National Authority for Scientific Research (NCBR)

Spain
Instituto de Salud Carlos III
Ministry of Economic Affairs and Digital Transformation

Sweden
Formas
Swedish Research Council (SRC)

Switzerland
​Swiss National Science Foundation (SNSF)

Turkey
Scientific and Technological Research Council of Turkey (TÜBİTAK)

United Kingdom
Medical Research Council (MRC)

Supported projects

In total 19 project consortia with a total of 96 research groups from 16 countries were awarded funding within the 3rd JPIAMR Joint Call “Transmission Dynamics” to bridge the knowledge gap on AMR transmission mechanisms. The total funding amount was 28,1 M€. Click on the project titles in the list below to learn more about each project.

The outputs, outcomes and the impact generated by the projects supported have now been published in a report. The report highlights the effect of supporting excellent science through transnational research collaborations.

Download the report (pdf 1 MB): 2016 call on AMR Transmission Dynamics: Research outputs, outcome and impact of the projects