Joint Programming Initiative on Antimicrobial Resistance

JPI – AMR Workshop in Oslo October 12-13 2016

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Surveillance is a key component of any strategy to counteract the spread and consequences of antimicrobial resistance (AMR). Many developed countries have surveillance in place based on data from clinical submissions, and the One Health concept is increasingly adopted for the surveillance of samples from feed, animals, food and the environment. However, our understanding of AMR epidemiology is still limited both geographically and ecologically.
The 2014 WHO report on AMR surveillance demonstrated that AMR surveillance at a global level is still in its infancy. The Global Antimicrobial Resistance Surveillance System (GLASS) will start early implementation in 2016.
The Joint Programming Initiative on Antimicrobial Resistance (JPI – AMR) is a research funding mechanism for AMR established among supportive countries with assistance from the EU. The scope of the activity is defined by the Strategic Research Agenda (SRA). The need for research concerning AMR surveillance is recognized in Topic C of the SRA:

Focus:  The establishment of an international, standardized surveillance programme for A and antibiotic use in human, and agricultural settings.
Objectives:     To perform operational research on the standardization and extension of existing surveillance systems

Activities:     To perform a pilot study on the feasibility of a global phenotypic and genotypic surveillance programme for AMR. So far, no funding calls have been issued within Topic C of the SRA.

Purpose AMR surveillance should provide data for safe patient management and protection against further spread of resistance. Present surveillance systems have severe limitations in their ability to estimate the individual and collective health burden of AMR as well as the effect of interventions for containment. Novel technologies will enable us to collect detailed information from various sources, but their role in ongoing surveillance activities remains to be determined. There is a need to expand and refine our surveillance programs, but knowledge on the optimal design and use of data is missing. The purpose of the workshop is to explore how surveillance systems can be developed to support scientific research, and how science can fill knowledge gaps to optimize surveillance.
Format The workshop will be hosted by the Norwegian Research Council as a lunch-to-lunch meeting for invited participants on October 12-13 in Oslo, Norway. The discussion will revolve around selected keynote lectures, breakout sessions and plenary discussions. Day 1 (after lunch):

  • Welcome and scope of the workshop
  • Gunnar Skov Simonsen (University of Tromsø, Norway)
  • The use of AMR surveillance data in scientific research – Opportunities and limitations
  • Liselotte Diaz Högberg (European Centre for Disease Prevention and Control, Sweden)
  • The global transition from phenotypic to genotypic AMR surveillance – How do we get there?
  • Neil Woodford (Public Health England, UK)
  • Breakout session in two groups to identify knowledge gaps in AMR surveillance and suggest funding calls for scientific research to amend these
    • AMR surveillance for patient management
    • Hajo Grundmann (Universitätsklinikum Freiburg, Germany)
    • AMR surveillance in non-human reservoirs
    • Bruno Gonzalez-Zorn (Complutense University, Spain)

Day 2 (before lunch)

  • Novel technologies and strategies for surveillance
  • David Aanensen (Imperial College, UK)
  • Reports from breakout sessions
    • The interplay between surveillance and science to optimize patient management
    • Hajo Grundmann (Universitätsklinikum Freiburg, Germany)
    • The interplay between surveillance and science to contain non-human AMR reservoirs

Bruno Gonzalez-Zorn (Complutense University, Spain)

  • Plenary discussion on future JPI-AMR funding call for AMR surveillance.
  • Martin Steinbakk (Norwegian Institute of Public Health, Norway)