Joint Programming Initiative on Antimicrobial Resistance

Why a JPI on AMR?

In the past seventy years, since their discovery, antibiotics have saved millions of lives from once-deadly diseases. For instance, antibiotics have paved the way for interventions that were previously impossible due to the high risk of patients succumbing to post-operative infections. Also, many treatments in modern medicine, such as organ transplants or cancer treatment, would be impossible without the use of antibiotics to prevent infections that can occur due to immunosuppression.

Through use and misuse of antibiotics, bacterial resistance continues to spread making antimicrobial drugs (including antibiotics) ineffective. Hence, the current situation is very grim. A British Committee, on behalf of the UK Government, found that presently in the US and Europe alone, 50,000 deaths per year can be related to antimicrobial resistance. And these figures are set to rise. The prediction is that by 2050, 10 million people will die each year due to drug resistant infections that will cost the society 100 billion dollars.

Joint collaborative actions, maximising research efforts and benefiting from the exchange of best practise, are crucial to tackle this problem. At the moment:

  • Few new drugs are being developed
  • There is excessive use of antibiotics
  • Resistance continues to spread
  • Funding and research efforts are dispersed

All this leads to a global societal problem, which will spiral out of control without action. JPIAMR aims to align resources by creating a collaborative platform, maximising existing and future efforts to combat AMR.

By working together in a JPI, we could achieve:

  • New preventative and therapeutic approaches
  • AMR relevant research elements more embedded in health service and care infrastructure
  • A reduction of inappropriate consumption of antibiotics in humans and animals
  • A positive impact on treatment, care and quality of life
  • Increased visibility of the burden of AMR and the benefits of research
  • A catalytic effect on the development on national and international strategies